Excision with Temporary Interphalangeal Joint Pin Fixation for Toe Ganglion Cysts

Background@#Toe ganglion cysts are often symptomatic and recurrent. Communicating lesions between ganglion cysts and the interphalangeal joint (IPJ) or tendon sheath make it difficult to prevent a recurrence. Temporary restriction of the joint and tendon motion can facilitate surgical site healing. This study analyzed the clinical results of temporary pin fixation of the IPJ after toe ganglion cyst excision. @*Methods@#Sixteen patients with symptomatic toe ganglion cysts underwent surgical treatment. Excision alone was initially performed on 10 patients. Six patients underwent temporary pin fixation of the IPJ after ganglion cyst excision. Repeat excision with pin fixation was performed for recurrence in two patients after excision only. Clinical evaluations and postoperative complications were analyzed. @*Results@#Fourteen of 16 toe ganglion cysts were located near the IPJ. Two cysts not adjacent to the joint completely healed after excision alone. Seven of 14 cysts near the joint recurred after initial excision alone and required repeated reoperation. Eight cysts did not recur after excision with pin fixation, including 2 that recurred after excision alone. @*Conclusions@#Temporary IPJ pin fixation after excision for ganglion cysts can be effective for preventing the recurrence of ganglion cysts adjacent to toe IPJ.

More than Five-Year Follow-Up Results of Nonoperative Treatment of Lateral Ankle Instability Patients Who Were Recommended Surgery / 대한정형외과학회잡지

Purpose@#This study analyzed the follow-up results of lateral ankle instability patients without surgery that were recommended surgery from other hospitals. @*Materials and Methods@#From May 2009 to December 2016, a retrospective study was conducted on 55 chronic lateral ankle instability patients at least five years of follow-up and an average of seven years or more. Nonoperative treatment was performed after one time of rehabilitation exercise training at the authors’ hospital. At the final follow-up, a physical examination and sports activity survey were done.Visual analogue scale (VAS), Foot Function Index (FFI), and Foot and Ankle Ability Measure (FAAM) scale were measured, respectively. For 37 patients who revisited, an anterior drawer test was done. In addition, the progression of arthritis was confirmed by a weight-bearing radiographic examination and instability was checked in stress radiographic examination. @*Results@#The average follow-up period of the 55 patients was 88.78 (60–136) months. The average VAS was 0.98 (0–4). None of the patients had restrictions of activities of daily living. For 37 patients who revisited, at the final follow-up, the mean FFI score was 11.27 (1–45), and the FAAM subscale scores were 79.35 (activities of daily living subscale) and 27.08 (sports subscale), respectively. As a result of the physical examination, the mean grade of anterior drawer test decreased from 2.08 at the first visit to 2.02 at the final follow-up. At the final follow-up, radiological examination showed no case of progression of degenerative arthritis of the ankle joint. The average value of anterior drawer stress X-ray was measured from 5.64 mm at the first visit to 5.47 mm (contralateral side 4.99 mm) at the final follow-up, and the average value of varus stress X-ray was measured from 12.03° at the first visit to 13.62°(contralateral side 10.62°) at the final follow-up. @*Conclusion@#In lateral ankle instability patients with nonoperative treatment after an average follow-up of more than seven years, ankle functions were good. There were no cases of progression to degenerative arthritis on radiological examination.

Validation of Electronic Foot Function Index in Patients with Foot and Ankle Disease: A Randomized, Prospective Multicenter Study / 대한족부족관절학회지

PURPOSE: To evaluate the efficiency of the electronic foot function index (eFFI) through a prospective, random based, multi-institutional study. MATERIALS AND METHODS: The study included 227 patients ranging in age from 20 to 79 years, visited for surgery in different 15 institutes, and agreed to volunteer. The patients were assigned randomly into a paper-based evaluated group (n=113) and tablet-based evaluated group (n=114). The evaluation was done on the day of hospital admission and the method was changed on the second day of surgery and re-evaluated. PADAS 2.0 (https://www.proscore.kr) was used as an electronic evaluation program. RESULTS: There were no differences in age and sex in both groups. The intraclass correlation coefficient (ICC) evaluation revealed an eFFI ICC of 0.924, showing that both results were similar. The evaluation time was shorter in the tablet-based group than the paper-based group (paper vs tablet, 3.7±3.8 vs 2.3±1.3 minutes). Thirty-nine patients (17.2%) preferred to use paper and 131 patients (57.7%) preferred the tablet. Fifty-seven patients (25.1%) found both ways to be acceptable. CONCLUSION: eFFI through tablet devices appears to be more constant than the paper-based program. In addition, it required a shorter amount of time and the patients tended to prefer the tablet-based program. Overall, tablet and cloud system can be beneficial to a clinical study.

Usefulness of Computed Tomography on Distal Tibia Intra-Articular Fracture Associated with Spiral Tibia Shaft Fracture

PURPOSE: The purpose of this study is to evaluate the usefulness of computed tomography (CT) for spiral tibia shaft fracture by analyzing associated distal tibia intra-articular fractures diagnosed by CT only which met the indication of surgical fixation and were fixed. MATERIALS AND METHODS: Ninety-five spiral tibia shaft fractures with preoperative ankle plain radiographs and CT were analyzed retrospectively. The incidence and type of associated distal tibia articular fractures were evaluated by reviewing ankle plain radiography and CT. The number of fractures diagnosed by CT that correspond with the indication of fixation and that were actually fixed were analyzed. RESULTS: Among 95 spiral tibia shaft fractures, 62 cases (65.3%) were associated with distal tibia intra-articular fracture. There were 37 cases of posterior malleolar fracture, 5 cases of avulsion fracture of the distal anterior tibiofibular ligament, 5 cases of medial malleolar fracture, and 15 cases of complex fracture. Among 52 posterior malleolar fractures including complex fracture, 20 cases were diagnosed by ankle plain radiograph. Of these 20 cases, 16 posterior malleolar fractures (80.0%) met the indication of surgical fixation, and 14 cases were actually fixed with a screw. Among 32 posterior malleolar fractures diagnosed by CT only, 26 cases (81.3%) met the indication of surgical fixation and 18 cases (56.3%) were fixed by screw. CONCLUSION: Approximately 50% of associated fractures were diagnosed by CT only and more than 80% of associated posterior malleolar fractures met the indication of surgical fixation and among these fractures, 18 cases (56.3%) were actually fixed by screw. This result suggests that CT is useful in diagnosis and treatment of distal tibia intra-articular fracture associated with spiral tibia shaft fracture.

Usefulness of Edinburgh Postnatal Depression Scale for Postpartum Depression / 대한주산의학회잡지

PURPOSE: Postpartum depression (PPD) is a common postnatal problem. PPD has a negative influence on maternal functioning and child development. We examined the result of Edinburgh Postnatal Depression Scale (EPDS) after delivery. METHODS: Three hundred two postpartum mothers were enrolled in the study. The Korean version of EPDS was completed and scored at postpartum visits. Mothers whose score was 10 or more were classified as an EPDS positive for PPD. We reviewed their medical records and determined risk factors for positive EPDS result. RESULTS: The positive rate of EPDS was 27.8% (84/302). Among various factors, a newborn's body weight more than 4.0 kg was statistically related to the positive result. The positive rate of EPDS was significantly higher when performed within postpartum 60 days than after postpartum 60 days. Among 84 positive women, only three mothers visited a psychiatric clinic for further evaluation and management of PPD. CONCLUSION: The EPDS was a useful tool for PPD screening. Obstetricians should consider an EPDS for effective screening of PPD. It would be the next important issue to encourage a screening positive mother to visit a psychiatric clinic.

A case of pseudomembranous colitis associated with antituberculosis therapy in a patient with tuberculous meningitis / 동물의과학연구지

Pseudomembranous colitis (PMC) is known to be associated with the long-term administration of antibiotics, which alter normal gastrointestinal flora and allow overgrowth of Clostridium difficile. However, antituberculosis agents are rarely reported as a cause of this disease. Besides, most cases of antituberculosis agent-induced PMC have been observed in patients with pulmonary tuberculosis but not with tuberculous meningitis. This report presents a case of PMC associated with antituberculosis therapy in a patient with tuberculous meningitis. A 29-year-old female patient was admitted due to headaches and diplopia that had lasted for 2 weeks. She had not recently received antimicrobial therapy. She was diagnosed with tuberculous meningitis by cerebrospinal fluid findings and neurologic examination, including brain imaging study. She was treated with standard antituberculosis agents (HERZ regimen: isoniazid, ethambutol, rifampicin, and pyrazinamide). After 11 days of HERZ, she developed a fever, sudden widespread skin eruption, and elevation of liver enzymes. Considering adverse drug reactions, antituberculosis agents were stopped. One week later, her symptoms were relieved. Thus, antituberculosis agents were reintroduced one at a time after liver function returned to normal. However, she presented with frequent mucoid, jelly-like diarrhea, and lower abdominal pain. Sigmoidscopy revealed multiple yellowish plaques with edematous mucosa, which were compatible with PMC. She was treated with oral vancomycin considering drug interactions. Symptoms were relieved and did not recur when all antituberculosis agents except pyrazinamide were started again. Therefore, when a patient complains of abdominal pain or diarrhea after initiation of antituberculosis therapy, the physician should consider the possibility of antituberculosis agent-associated PMC.

A Case of Primary Aortoenteric Fistula Mimicking Ulcer Bleeding / 대한소화기학회지

Primary aortoenteric fistula (PAEF) is a rare disease with a high mortality rate due to massive hemorrhaging and diagnostic difficulties. Although hemorrhagic regions can be identified by endoscopy, it is difficult to diagnose PAEF by this method. If PAEF is suspected, endoscopic procedure should be terminated and abdominal CT should be performed. Overlooking the herald bleeding of PAEF can lead to massive bleeding and death. An 85-year-old previously healthy male presented with a complaint of melena. Gastrointestinal endoscopy identified a hemorrhagic site in the third portion of the duodenum and endoscopic hemostasis was performed. However, during the procedure, it became apparent that the hemorrhage was probably not the result of a simple duodenal ulceration and abdominal CT was performed immediately. An aortic aneurysm connected to the duodenum was identified, confirming the diagnosis of PAEF. However, the patient died of massive hemorrhaging before an operation could be performed.

Clinical and radiological findings in community-acquired pneumonia: A comparison between viral and bacterial infection / 동물의과학연구지

Effective treatment for community-acquired pneumonia (CAP) requires administration of appropriate empirical therapy based on etiologic, clinical, and radiological features. However, in Korea, CAP is poorly characterized, and data on viral CAP are particularly sparse. Therefore, improper use of antibiotics is common, and is detrimental the potential for development of bacterial. Thus, we investigated clinical and radiological findings for discrimination of viral CAP from bacterial CAP. Etiologic, clinical, and radiological data from 467 patients with CAP at Chungbuk National University Hospital from October 2010 to September 2011 were analyzed retrospectively. Viruses were identified in 23 cases (11.4%); the influenza virus A was the most common virus detected (N=18, 25.4%), followed by the respiratory syncytial virus A (N=14, 17.9%). Bacteria were identified in 48 cases (23.8%); Streptococcus-pneumonia was the most common (N=24, 25.5%), followed by Staphylococcus aureus (N=20, 21.3%). Depending on hospitalization time, the following significant differences were observed between viral and bacterial CAP: on admission, (1) high fever (> or = 38.5degrees C), (2) purulent sputum, (3) white blood cell count, (4) C-reactive protein levels, (5) and bilateral lung involvement on chest X-ray were higher in bacterial CAP; and at discharge, (1) duration of high fever and (2) radiologic improvement within three days were higher in viral CAP. Regarding seasonal patterns, both viruses and bacteria have been identified with relative frequency in the winter season. This study described the etiological, clinical, and radiological findings of viral and bacterial CAP. Conduct of additional large-scale, prospective investigations will be required in order to improve the appropriate treatment of CAP.

A Rare Combination of the Left Circumflex Coronary Artery Fistula Connecting a Dilated Coronary Sinus with Persistent Left Superior Vena Cava and Multiple Arteriovenous Fistulae

Coronary artery fistula (CAF) is an abnormal communication between an epicardial coronary artery and a cardiac chamber, major vessel or other vascular structures. This report presents a rare case of CAF in which a dilated left main trunk and proximal circumflex coronary artery are connected to a dilated coronary sinus. There were also two other fistulae and persistent left superior vena cava. The coronary fistula was managed conservatively.

The diagnostic efficacy and safety of endobronchial ultrasound-guided transbronchial needle aspiration as an initial diagnostic tool

BACKGROUND/AIMS: Real-time, convex probe endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) is used for the staging of malignant mediastinal lymph nodes. We evaluated the diagnostic efficacy and safety of EBUS-TBNA when used as an initial diagnostic tool. METHODS: We retrospectively studied 56 patients who underwent EBUS-TBNA as an initial diagnostic tool between August 2010 and December 2011. Procedure purpose were classified into four categories: 1) intrathoracic masses adjacent to the central airway; 2) enlarged lymph nodes for concurrent diagnosis and staging in suspected malignancy; 3) enlarged lymph nodes in suspected malignancy cases with inability to perform percutaneous core needle biopsy (PCNB); and 4) solely mediastinal masses/lymph nodes in lieu of mediastinoscopy. RESULTS: The diagnostic accuracy of EBUS-TBNA regardless of procedure purpose was calculated to be 83.9%. Furthermore, the diagnostic accuracy of malignant disease was significantly higher than benign disease (93.9% vs. 70.6%, p < 0.001). The diagnostic accuracy of EBUS-TBNA for each disease is as follows: tuberculosis, 50%; sarcoidosis, 60%; aspergillosis, 100%; lung abscess, 100%; lung cancer, 93%; and lymphoma, 100%. There were minor complications in seven patients during the EBUS-TBNA procedure. The complications included mild hypoxia and bleeding. CONCLUSIONS: In conclusion, EBUS-TBNA is a useful initial diagnostic tool for both benign and malignant diseases. EBUS-TBAN is also a very safe procedure and less invasive compared to mediastinoscopy or PCNB.

Reverse Superficial Sural artery flap for the Reconstruction of Soft Tissue Defect on Posterior side of heel exposing Achilles tendon

PURPOSE: Soft tissue defect on posterior side of heel exposing Achilles tendon is vulnerable and require thin flap to improve aesthetic and functional results. Reverse superficial sural artery flap is simple and fast procedure, and it can preserves major arteries, supplies reliable constant blood, causes less donor site complication. Authors reviewed our cases and report the clinical results. MATERIALS AND METHODS: Nine cases of soft tissue defects on the posterior side of heel exposing Achilles tendon were treated with distally based superficial sural artery flap. There were 6 male and 3 female and mean age was 48.4 years. The size of flap was from 4x4 cm to 10x15 cm and mean follow-up period was 23 months. Flap survival, postoperative complications were evaluated. RESULTS: All flaps were survived completely without necrosis. There was one case of partial wound dehiscence that needed debridement and repair, and other one case had recurrent discharge that was healed after removal of calcaneal plate. All patient showed acceptable range of ankle motion. CONCLUSION: Authors suggest that the reverse superficial sural artery flap could be one of the useful treatment options for the soft tissue defect on posterior side of heel exposing Achilles tendon.

Invasive Aspergillosis Involving the Lungs and Brain after Short Period of Steroid Injection: A Case Report / 결핵및호흡기질환

Invasive pulmonary aspergillosis (IPA) has emerged as a severe infection in patients with immunocompromised hosts. However, recently, several IPA cases, without an apparent predisposition to immunodeficiency, has been reported. A 72-year-old woman was admitted for evaluation of general weakness and poor oral intake. She reported no medical history, except for intraarticular injection of a corticosteroid for joint pain for the duration of two months. A chest radiography revealed multiple cavitary nodules in both lungs. Examination of specimens, obtained by percutaneous needle biopsy, led to a diagnosis of invasive aspergillosis. Brain magnetic resonance imagining revealed numerous peripheral thin enhancing cystic nodules in both cerebral hemispheres. We initiated intravenous administration of amphotercin B. However, the patient died after nine days. Here, we report an invasive aspergillosis case, which involves the lungs and brain after a short period of steroid injection.

A Case of Lingual Thyroid Treated by 131I Ablation

A lingual thyroid is a rare developmental anomaly caused by the failure of the descent of the thyroid gland anlage early in the course of embryogenesis. The incidence of lingual thyroid has been reported to be 1/100,000. Lingual thyroid is often asymptomatic but may cause dysphagia, dysphonia, upper airway obstruction and hemorrhage. In this report, we described the case of a 50-year-old women experiencing lingual thyroid who had subclinical hypothyroidism. She underwent successful 131I ablation and has done well on thyroid hormone replacement therapy.

Metastatic Renal Cell Carcinoma in a Supraclavicular Lymph Node with No Known Primary: A Case Report / Journal of the Korean Cancer Association, 대한암학회지

Although metastasis is relatively frequent in cases of renal cell carcinoma (RCC), metastasis in the cervical or supraclavicular lymph node (LN) is relatively rare. Moreover, cases of metastatic RCC with a non-identifiable kidney mass are extremely rare. Here, the authors report a case of metastatic RCC in a supraclavicular LN without a primary kidney lesion. A 69-year-old man presented with a progressively enlarging right supraclavicular mass. Incisional biopsy of the affected supraclavicular LN was performed, and histological examination revealed metastatic RCC. However, no tumor was found in either kidney, despite various examinations. The patient was treated with radiotherapy followed by sunitinib. After three months on sunitinib, a follow-up computed tomography scan revealed that the supraclavicular LN had markedly decreased, and after 20 months, the disease had not progressed. This case suggests that, even when there is no primary kidney lesion, clinicians must consider the possibility of metastatic RCC when evaluating patients with clear cell carcinoma with an unknown primary site.

Results of Non-Operative Treatment of the Zone I, II Fifth Metatarsal Base Fracture / 대한족부족관절학회지

PURPOSE: To evaluate the results of conservative treatment of zone I, II 5th metatarsal base fracture. MATERIALS AND METHODS: Between May 2004 and June 2010, a total of 58 patients of zone I, II 5th metatarsal base fractures were included in this study. The mean length of follow-up was 13.5 months (12~36 months). All of the patients were treated with full-weight-bearing short leg cast immobilization for 4 weeks and wooden sole shoes for 4 weeks. The results were evaluated about the radiographic union, the midfoot scale of American Orthopaedic Foot and Ankle Society (AOFAS), the tenderness on fracture site and other complications. RESULTS: All patients were able to return to their prior levels of activity. The mean time for union as shown on radiographs was 45.5 days, and the mean midfoot scale of AOFAS was 99.7 points. There were no nonunions or refractures during the follow-up. CONCLUSION: The conservative treatment with full-weight-bearing short leg cast and wooden sole shoes seems to give good results for zone I, II 5th metatarsal base fracture.

Changes of Clinical Benefit and Subjective Wellbeing after Switching to Extended Release Quetiapine Furmate (Quetiapine XR) in Patients with Schizophrenia: Naturalistic, Observational Study (CLIMAX Study) / 대한정신약물학회지

OBJECTIVE: The aim of this study was to demonstrate changes of clinical benefit and subjective wellbeing after once-daily extended release quetiapine furmate (quetiapine XR) in patients with schizophrenia. METHODS: In a naturalistic, observational, and multicentric study, 1,494 patients with schizophrenia who switched to quetiapine XR (flexible dosing) due to insufficient efficacy or intolerance were recruited. Clinical Global Impressions-Clinical Benefit (CGI-CB), CGI-Severity (CGI-S), CGI-Improvement (CGI-I) and Subjective Wellbeing under Neuroleptic Treatment Scale (SWN-K) were assessed at baseline and after 8 weeks treatment. We also examined factors related to changes of CGI-CB and SWN-K scores using linear regression analysis. RESULTS: Among 1,494 patients, 1,342 patients (89.8%) completed this study and 1,204 patients (80.6%) without protocol violation were included in the analysis. The mean dose of quetiapine XR was 416.9+/-205.8 mg/day at the initiation and continuously increased to 591.6+/-228.3 mg/day until week 5. At the endpoint, the mean dose of quetiapine XR was 580.24+/-382.24 mg/day. Both CGI-CB and CGI-S scores were significantly decreased after 8 weeks (both p<0.0001) and 745 patients (61.9%) achieved clinical benefit. Mean CGI-I scores were 2.49+/-0.80 and the response rate defined as CGI-I< or =2 was 51.6%. Subjective wellbeing scores were increased after 8 weeks (p<0.0001). Improvements of CGI-CB and subjective wellbeing were associated with quetiapine XR dosages as well as age and baseline scores. CONCLUSION: After switching to quetiapine XR, 61.9% of patients with schizophrenia who had a history of unsatisfactory treatment (efficacy or tolerance) showed clinical benefit and subjective wellbeing was significantly increased. Regarding that dosages of quetiapine XR were associated with improvements of clinical benefit and subjective wellbeing, active treatment strategies with higher dosages of quetiapine XR could be suggested in the real field.

An fMRI Study Regarding the 'Theory of Mind' in Korean Schizophrenic Patients Using a First Order False Belief Task / 신경정신의학

OBJECTIVES: The aim of this study was to investigate brain activation during a Korean language-based 'theory of mind (TOM)' task and fMRI in Korean schizophrenic patients. METHODS: Fourteen Korean schizophrenic patients and 15 normal controls participated in this study. For all participants, several clinical states and psychosocial functions were evaluated. The subjects were then scanned while performing Korean language-based fMRI tasks. The tasks were comprised of conditions-first order false belief (TOM task), physical causality, and unrelated situations. Imaging data were analyzed using SPM2 software (uncorrected p<0.005, extent threshold kappa=10). RESULTS: 1) Compared with the control group, the patient group showed significantly poorer performance on the TOM task, and no significant correlation between TOM and empathic abilitiesy. 2) In the patient group, there were no significantly activated brain regions associated with the TOM task as compared to the physical causality task. With respect to between-group differences, the patient group showed significantly less activation of the left medial frontal region (primarily BA 8) and signifcantly different activation of the left precuneus (BA 7) associated with the TOM task. CONCLUSION: These results suggest that Korean schizophreniac patients show different brain activity associated with TOM functions, especially with respect to the Korean language-based first order false belief tasks.

The Properties of Temperament, Character and Stress Response in Patients with Irritable Bowel Syndrome / 신경정신의학

OBJECTIVES: The purpose of this study was to assess the specific properties of temperament, character and stress response in patients with irritable bowel syndrome compared to those with peptic ulcer disease and healthy controls. METHODS: We studied nineteen subjects with irritable bowel syndrome, twenty-six subjects with peptic ulcer disease and thirty-three healthy control subjects. All subjects completed Temperament and Character Inventory (TCI), Stress Response Inventory (SRI) and questionnaire of demographic characteristics and several variables. RESULTS: From the results of the TCI's, the scores of harm avoidance (HA1, HA2, HA3, HA4, HA total) were significantly higher in the irritable bowel syndrome group than those of the peptic ulcer disease group or the healthy control group. In contrast, the scores of self directedness (SD3) were lower in the irritable bowel syndrome group than the healthy control group. From the results of the SRI's, somatization, anger, fatigue and frustration were significantly higher in the irritable bowel syndrome group. No significant difference was found in TCI and SRI results between the peptic ulcer disease group and the healthy control group. CONCLUSION: The results of this study suggest that patients with irritable bowel syndrome show specific properties of temperament, character and stress response compared with either peptic ulcer disease patients or healthy controls.

The Relationship between Intraocular Pressure and Cardiovascular Risk Factors

PURPOSE: To evaluate the relationship between intraocular pressure (IOP) and cardiovascular risk variables in healthy Koreans adjusted for age and mean blood pressure. METHODS: A total of 1477 healthy participants underwent automated multi-phasic test, including tonometry, automated perimetry, fundus photography, blood pressure, and cardiovascular risk variables such as total cholesterol, high density lipoprotein, triglyceride, and blood glucose. The subjects were divided into six age groups by decades ranging from 20~29 years to over 70 years. The relationship between IOP and cardiovascular risk variables was examined using multiple regression analysis. RESULTS: The mean age of participants was 49.0 years, and 778 (52.7%) of participants were men. The mean IOP was 15.8+/-3.2 mmHg, and was significantly higher in men than in women (p0.05). CONCLUSIONS: As increased IOP was associated with cardiovascular risk variables, it is necessary to control increased total cholesterol, triglyceride, and blood glucose levels in the normal population to prevent or control the IOP elevation.

Clinical Analysis of Congenital Exotropia

Constant exotropia is uncommon during the first year of life.We investigated characteristics, surgical outcome and associated ocular abnormalities in patients who had an exodeviation during the first year of life. The charts of 18 patients who were diagnosed as congenital exotropia before 1 year old were reviewed.We etrospectively analyzed 10 healthy patients who did not have associated systemic or ocular abnormalities and were followed for at least 3 months after surgery. The mean follow-up period was 1.2 years[range, 3 months to 3.5 years]and all of them had an exodeviation of 25 prism diopter[PD]or more[mean, 37.5PD, SD 10.6PD].Preoperative DVD and inferior oblique muscle overaction were found in 1 patient respectively. Surgery was performed in 9 cases and botulinum toxin was injected in 1 case.Seven patients[70%]showed stable alignment within 10PD with one operation and one patient required reoperation.Postoperative dissociated vertical deviation and inferior oblique muscle overaction were found in each 1 patients. Congenital exotropia has large deviation and may be associated with inferior oblique muscle overaction or dissociated vertical deviation as infantile esotropia and has stable alignment with single operation.But unlike infan-tile esotropia, nystagmus is extremely rare.